EN4 MYC inhibitor
EN4 MYC inhibitor(EN4 MYC inhibitor)
CAS: 1197824-15-9
化学式: C25H24N2O4
| 中文名 | EN4 MYC inhibitor |
| 英文名 | EN4 MYC inhibitor |
| 别名 | 化合物EN4 MYC INHIBITOR |
| 英文别名 | EN4 MYC inhibitor Benzamide, N-[2-(4-ethoxyphenoxy)phenyl]-4-[[(1-oxo-2-propen-1-yl)amino]methyl]- |
| CAS | 1197824-15-9 |
| 化学式 | C25H24N2O4 |
| 分子量 | 416.47 |
| 密度 | 1.202±0.06 g/cm3(Predicted) |
| 沸点 | 564.1±50.0 °C(Predicted) |
| 酸度系数 | 12.82±0.70(Predicted) |
| 存储条件 | -20℃ |
| 产品用途 | EN4 is a functional Covalent Ligand Targeting an Intrinsically Disordered Cysteine within MYC. EN4 functionally and covalently targets an intrinsically disordered region in MYC. EN4 directly targets MYC in cells and reduces MYC and MAX thermal stability. EN4 inhibits MYC activity, downregulates MYC targets, and impairs tumorigenesis. MYC is a major oncogenic transcriptional driver of most human cancers that has remained intractable to direct targeting because much of MYC is intrinsically disordered. |
| 参考资料 展开查看 | Boike L, Cioffi AG, Majewski FC, Co J, Henning NJ, Jones MD, Liu G, McKenna JM, Tallarico JA, Schirle M, Nomura DK. Discovery of a Functional Covalent Ligand Targeting an Intrinsically Disordered Cysteine within MYC. Cell Chem Biol. 2021 Jan 21;28(1):4-13.e17. doi: 10.1016/j.chembiol.2020.09.001. Epub 2020 Sep 22. PMID: 32966806; PMCID: PMC7854864. |
EN4 MYC inhibitor - 配置溶液浓度参考
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.401 ml | 12.006 ml | 24.011 ml |
| 5 mM | 0.48 ml | 2.401 ml | 4.802 ml |
| 10 mM | 0.24 ml | 1.201 ml | 2.401 ml |
| 5 mM | 0.048 ml | 0.24 ml | 0.48 ml |
最后更新：2024-01-02 23:10:35
供应商列表
现货供应
产品名: EN4 MYC inhibitor 去供应商网站查看 询盘CAS: 1197824-15-9
产地: 上海
规格: 98%
价格: 5mg 480,10mg 720,25mg 1440,100mg 4320
库存: 现货
电话: 18301782025
手机: 18301782025
电子邮件: 3008007403@qq.com
QQ: 3008007403
微信: 18301782025
产品描述: EN4 MYC inhibitor 98% MedMol 货号：S89228
现货供应
产品名: EN4 MYC inhibitor 去供应商网站查看 询盘CAS: 1197824-15-9
产地: 上海
规格: 98%
价格: 5mg 480,10mg 720,25mg 1440,100mg 4320
库存: 现货
电话: 18301782025
手机: 18301782025
电子邮件: 3008007403@qq.com
QQ: 3008007403
微信: 18301782025
产品描述: EN4 MYC inhibitor 98% MedMol 货号：S89228
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